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H763

Coat colour in dogs is controlled by a wide range of different genes working together.

10 working days

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Caractéristiques

Breeds

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Gene

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Year Published

Informations générales

Coat colour in dogs is controlled by a wide range of different genes working together. These genes are often referred to as ‘loci’. The Ticking, or T-Locus, corresponds to the usherin gene (USH2A), which helps control the development of the dog’s coat pattern. T-Locus mutations in dogs cause the development of alternating areas of white and pigmented hairs, which can result in two distinct patterns: Ticked and Roan. These traits are co-dominant (a dog carrying both the Ticked and Roan mutations will develop a combination of the two patterns), and both are dominant over a clear (unpatterned) coat.

Caractéristiques cliniques

A Ticked coat features pigmented spots in otherwise white areas of the body. These spots tend to be the most common on the legs and muzzle.

A Roan coat features a mostly even mixture of white and pigmented hairs on areas of the body that would otherwise be pure white.

Additional Information

Coat colour is an intricate trait that involves a combination of multiple different genes. Testing for a range of different loci will give the most complete prediction of a dog's coat colour genetics.

Références

Pubmed ID: 33539602; 33755696

Omia ID: 1216

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