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Dilute Coat Colour with Neurological Defects is a severe neurological disorder found in the Miniature Dachshund, resulting muscle weakness and lack of coordination as well as pale fur.
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Caractéristiques
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Year Published |
Informations générales
Dilute Coat Colour with Neurological Defects is a severe neurological disorder found in the Miniature Dachshund, resulting muscle weakness and lack of coordination as well as pale fur. It is caused by a recessive mutation to the gene MYO5A.
Caractéristiques cliniques
Affected puppies are born with a visibly dilute coat colour. Within the first weeks of age, they will present with neurological symptoms: an inability to keep the head upright or to lie down normally (instead falling over onto one side), and decreased response to environmental stimuli. The severity of the symptoms typically necessitates euthanasia on humane grounds.
Additional Information
Références
Pubmed ID: 34680875
Omia ID: 1501