Adult Onset Deafness EAOD (4 associated markers) – Border Collie

Early Adult Onset Deafness (EAOD) is a hearing disorder in Border Collies. While age-related hearing loss typically begins around 8–10 years, EAOD has an early onset at 3–5 years. For working Border Collies, EAOD is particularly problematic, as even slight differences in tone perception are essential for their ability to perform tasks. Therefore, even moderate hearing loss can significantly impact their working ability, though it does not have other serious (medical) consequences.

We test four genetic variants that are risk factors for progressive deafness in Border Collies. These variants are found in three genes: the USP31 gene, which is involved in mitigating tissue damage in the ear, the HS3ST2 gene, which may play a role in brain function and the RBBP6 gene, which plays an important role in ear development.

Gradual hearing loss is observed in dogs between the ages of 3 and 5 years, affecting both ears. You may notice the following signs and behavioural changes in your dog: changes in sleep patterns, changes in barking, increased startle responses to environmental factors, disobedience and/or fewer greetings all.