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While leopard complex spotting (LP; an incompletely dominant mutation) produces a collection of unique depigmentation patterns in the horse, other loci are responsible for modification of the extent of white.
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Caractéristiques
| Breeds | Cheval miniature, Poney des Amériques, Appaloosa, British Spotted Pony, Falabella, Knabstrupper |
|---|---|
| Gene | |
| Organ | |
| specimen | Hair, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Informations générales
While leopard complex spotting (LP; an incompletely dominant mutation) produces a collection of unique depigmentation patterns in the horse, other loci are responsible for modification of the extent of white. Pattern-1 (PATN1) is one of the indicated genes with a major modifying effect of LP for patterning. Horses with the more extreme white patterns (termed leopard and few-spot) have a parent with the same level of patterning, making it a single dominant mode of inheritance. This modifier has been termed PATN1 for pattern-1 or the first LP pattern modifier.
PATN1 is caused by a dominant mutation to the gene RFWD3.
Caractéristiques cliniques
Les chevaux avec LP et PATN1 ont une grande quantité de motifs blancs tandis que les chevaux avec LP mais sans PATN1 ont une faible quantité de motifs blancs.
Additional Information
Références
Pubmed ID: 26568529
Omia ID: