57,48 47,50 hors TVA

K316

Progressive Retinal Atrophy (PRA) is a large group of genetic diseases in which the retina gradually degenerates over time, causing a progressive loss of vision.

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Caractéristiques

Breeds

, ,

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

Informations générales

Progressive Retinal Atrophy (PRA) is a large group of genetic diseases in which the retina gradually degenerates over time, causing a progressive loss of vision. This variant of the disease, known as bPRA, occurs occurs in the Bengal, Savannah and Toyger breeds. It is caused by a recessive mutation to the gene KIF3B.

Caractéristiques cliniques

Cats with Progressive Retinal Atrophy (PRA) can show symptoms at an early age (a few weeks after birth). The symptoms progress slowly and cats can have very compromised vision by approximately 2 years of age. Blind cats tend to have changes in behaviour (e.g. more vocal and more attached to their owners). Their pupils are usually more dilated in lighting conditions and affected cats also tend to carry their whiskers in a more forward position.

Additional Information

Références

Pubmed ID: 32386558

Omia ID: 2267

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