57,48 47,50 hors TVA

H698

As in humans, Narcolepsy in dogs is a long-term sleep disorder resulting in lethargy and sudden bouts of sleep.

10 working days

Excl €5,95 shipping and administration per order (incl. VAT)

Caractéristiques

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

Informations générales

As in humans, Narcolepsy in dogs is a long-term sleep disorder resulting in lethargy and sudden bouts of sleep. Canine narcolepsy is a recessive disorder caused by a mutation to the HCRTR2 gene. The variant analysed in this test is found in the Labrador Retriever. Related variants occur in the Doberman Pinscher and the Dachshund.

Caractéristiques cliniques

Narcolepsy is neither progressive nor life-threatening. Narcolepsy affected canines may show signs between 4 weeks to 6 months of age. Affected canine fall asleep faster than normal dogs and cannot stay awake for an extended period of time. In respons to emotional stimulus, affected canines may experience cataplexy: a sudden loss of muscle tone without loss of consciousness. First signs of cataplexy are buckling of both hindlimbs and drooping of the neck.

Additional Information

Références

Pubmed ID: 10458611

Omia ID: 703

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