€57,48 €47,50 hors TVA
Haemophilia A, also known as Factor VIII Deficiency, is the most prevalent bleeding disorder in dogs.
15 working days
Excl €5,95 shipping and administration per order (incl. VAT)
Caractéristiques
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Informations générales
Haemophilia A, also known as Factor VIII Deficiency, is the most prevalent bleeding disorder in dogs. This X-linked recessive condition is triggered by a mutation in the gene F8, which severely compromises the blood’s clotting ability. Dogs affected by Haemophilia A may exhibit symptoms like spontaneous internal bleeding or uncontrolled bleeding following injuries or surgical procedures. These manifestations are a result of the impaired clotting mechanism in the bloodstream. As an X-linked recessive disorder, it predominantly affects male dogs, while female dogs usually act as carriers.
This specific variant is found in the German Shepherd and is known as HEMA-1. A different variant is found in other breeds including the Irish Setter, Miniature Schnauzer, Boxer, Old English Sheepdog, and the Rhodesian Ridgeback.
Caractéristiques cliniques
Common clinical signs in dogs included: bleeding from the mouth, subcutaneous and intramuscular haematomas and lameness.
Additional Information
This test is patented in certain countries. We offer our clients two options for this test because we are not allowed to perform the test in our laboratory. Firstly, the test can be ordered through a licensee of the patent owner. As a second option, the test can be forwarded to a partner laboratory in non-patented territory.
This is an X-linked disease.
This test is performed by an external laboratory. CombiBreed takes care of the mediation between you as a customer and the external laboratory. In this case, CombiBreed cannot be held liable for the behaviour of the client and/or contractor.
Références
Pubmed ID: 21949058
Omia ID: 437