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Canine Scott Syndrome (CSS), also called Platelet Factor X Receptor Deficiency or Hemorrhagic Diathesis, is caused by a defect in platelet function.
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Caractéristiques
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Écouvillonnage, sanguin EDTA, sanguine hépariné, sperme, tissu |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Informations générales
Canine Scott Syndrome (CSS), also called Platelet Factor X Receptor Deficiency or Hemorrhagic Diathesis, is caused by a defect in platelet function. Platelets, also called thrombocytes, play an important role in blood coagulation. The disease is caused by a recessive mutation to the gene ANO6.
Caractéristiques cliniques
In dogs with CSS, common symptoms include postoperative bruising and hematoma formation at surgical sites. While these symptoms are usually mild, life-threatening bleeding after surgery has been reported. As a result, affected dogs may require blood or platelet transfusions during surgery. If surgery is planned, it is important to inform the veterinarian. Nonsurgical bleeding can also occur, including recurrent episodes of epistaxis (nosebleeds) and bleedings affecting the joints or soft tissues. Despite the bleeding tendency, affected dogs are expected to have a normal lifespan.
Additional Information
Références
Pubmed ID: 26414452
Omia ID: 1353