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Anhidrotic Ectodermal Dysplasia (XHED) is a skin and tissue disorder that results in lack of hair and underdeveloped teeth, and can leave affected dogs vulnerable to parasites and infections.
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Caractéristiques
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Informations générales
Anhidrotic Ectodermal Dysplasia (XHED) is a skin and tissue disorder that results in lack of hair and underdeveloped teeth, and can leave affected dogs vulnerable to parasites and infections. It is caused by an X-linked recessive mutation to the gene EDA. The variant of the disease in this test is found in the German Shepherd. Other variants have been observed in the Dachshund and certain mixed breeds.
Caractéristiques cliniques
Affected dogs have no sweat glands or secondary hairs, and lack hair on the forehead and on the lower back. They also lack many teeth, with remaining teeth being unusually cone-shaped. Other complications from the condition can include chronic discharge from the eyes and nose, as well as susceptibility to airway infections and skin parasites.
Additional Information
Références
Pubmed ID: 16151697
Omia ID: 543