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Piebald – the presence of white spots or splotches on the coat – is caused by a mutation to the MITF gene, known commonly as the S-Locus (‘Spotting’ locus).
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Caractéristiques
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Informations générales
Piebald – the presence of white spots or splotches on the coat – is caused by a mutation to the MITF gene, known commonly as the S-Locus (‘Spotting’ locus). The mutation is dominant, and a dog carrying at least one copy of the mutant allele will show some degree of white spotting.
Caractéristiques cliniques
Absence/reduction of melanocytes results in various degrees of white spotting, including tiny white spots, large white spots and even complete white animals in for example the boxer.
Additional Information
La couleur du pelage est un trait complexe qui implique une combinaison de plusieurs gènes différents. Les tests pour une gamme de locus différents donneront la prédiction la plus complète de la génétique de la couleur du pelage d’un chien.
Les races spécifiques ne sont pas définies.
Références
Pubmed ID: 17906626
Omia ID: 214