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Cerebellar cortical degeneration (CCD) is a neurodegenerative disease process affecting many dog breeds.
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Caractéristiques
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Informations générales
Cerebellar cortical degeneration (CCD) is a neurodegenerative disease process affecting many dog breeds. The disease affects a specific area of the brain known as the cerebellum. In cerebellar degeneration, the cells within the cerebellum die, causing neurological symptoms in dogs.
This variant of the disorder, also known as Neonatal Cortical Cerebellar Degeneration (NCCD), is found in the Vizsla. It is caused by a recessive mutation to the gene SNX14.
Caractéristiques cliniques
L’âge d’apparition varie du néonatal au début précoce de semaines à des mois. Les symptômes comprennent une anomalie de la marche, une position large, un balancement, des tremblements musculaires avec l’alimentation et l’exécution d’activités, une inclinaison de la tête, une perte de coordination et une posture anormale.
Additional Information
Références
Pubmed ID: 27566131
Omia ID: 2034