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Hereditary Necrotising Myelopathy (HNM or ENM) is a degenerative neural disease.
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Caractéristiques
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Informations générales
Hereditary Necrotising Myelopathy (HNM or ENM) is a degenerative neural disease. The disorder is found in the Dutch Kooiker (Kooikerhondje) and is caused by a recessive mutation to the gene IBA57.
Caractéristiques cliniques
Affected dogs generally start displaying symptoms at approximately 4 years of age, though individual cases can start as early as 6 months or as late as 10 years. Symptoms of HNM include difficulty getting up and standing, a stiff and sometimes painful gait, muscle weakness, difficulty eating and drinking, excessive drooling, anorexia, depression and an altered voice.
Additional Information
Références
Pubmed ID: 37588046
Omia ID: 706