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Coat colour in cats is controlled by a wide range of different genes working together.
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Caractéristiques
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Écouvillonnage, sanguin EDTA, sanguine hépariné, sperme, tissu |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Informations générales
Coat colour in cats is controlled by a wide range of different genes working together. These genes are often referred to as “loci”. The C-Locus, a.k.a. Colour Locus, corresponds to the gene for tyrosinase (TYR). Recessive mutations to TYR can cause various degrees of Type 1 Oculocutaneous Albinism (OCA1), a failure to produce pigment, which leads to a silvery-white coat and light-coloured eyes. This can range between the distinctive point colouration of the Siamese cat, to full albinism.
The mutation analysed in this test, designated as “c2”, is one of two that results in a fully albino coat. Together with the “c” mutation, it is recessive to all other C-Locus alleles.
Caractéristiques cliniques
Affected cats are fully albino, with a white coat, blue eyes and a reddish pupil due to a lack of tapetum.
Additional Information
Coat colour is an intricate trait that involves a combination of multiple different genes. Testing for a range of different loci will give the most complete prediction of a cat's coat colour genetics.
Références
Pubmed ID: 27634063
Omia ID: 202