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Despite all being descendants of the grey wolf, the many breeds of the domestic dog are extremely diverse in terms of body size and weight.
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Caractéristiques
Breeds | |
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Gene | |
Organ | |
specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
Mode of Inheritance | |
Chromosome | |
Year Published |
Informations générales
Despite all being descendants of the grey wolf, the many breeds of the domestic dog are extremely diverse in terms of body size and weight. Size is a highly complex trait, influenced by a wide array of factors. However, research has shown that a significant part of body size variation in dog breeds can be linked to seven specific genetic markers. This test analyses for one of these markers.
The mutation analysed in this test is one of two located on the gene for growth hormone receptor (GHR). This mutation, designated as E191K or GHR(1), decreases body size and weight.
Caractéristiques cliniques
Dogs not carrying this mutation (GG) will tend to have a greater body size and weight. In turn, carrier dogs (one copy of the mutant allele; GA) will tend to be larger than affected dogs (two copies; AA)
Additional Information
This trait is of multifactorial origin; the described features are the result of a combination of factors from several genes and the environment.
Références
Pubmed ID: 24026177
Omia ID: