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Cats have several different possible serotypes (blood types): Type A, Type B and the more uncommon Type AB (sometimes known as Type C).
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Caractéristiques
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Year Published |
Informations générales
Cats have several different possible serotypes (blood types): Type A, Type B and the more uncommon Type AB (sometimes known as Type C). Type A is “normal”; Types B and AB can be caused by a number of recessive mutations to the gene CMAH.
Besides being relevant for medical issues such as blood transfusion, a cat’s serotype is significant for breeding. If a kitten with Serotype A is born to a mother with Serotype B, it is at risk from the A-targeting antibodies in the mother’s milk. This causes a potentially lethal reaction known as Feline Isoerythrolysis Neonatalis (IN) or “Fading Kitten Syndrome”.
This test analyses for the rare mutation a^c, which causes blood type AB. The a^c allele is recessive to N (Type A), but dominant to b (Type B).
Caractéristiques cliniques
Le système de groupe sanguin A/B est cliniquement important chez les chats parce que la reproduction et les transfusions mal adaptées peuvent causer des réactions hémolytiques représentant un danger pour la vie sans sensibilisation préalable. Par conséquent, une caractérisation génétique complète de tous les groupes sanguins félins est cruciale afin que les tests génétiques puissent rapporter avec précision le groupe sanguin d’une personne.
Additional Information
Due to the many possible mutations that can cause blood type B, it is not always possible to identify a cat's blood type through genetics alone.
The serological test (K712) directly determines your cat’s serotype: A (N/N), B (b/b) or AB (N/b). This can only be tested on a blood sample.
Références
Pubmed ID: 27171395
Omia ID: 119