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Fanconi Syndrome (FS) is a potentially severe kidney disorder that can cause dehydration, weight loss, and ultimately kidney failure.
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Caractéristiques
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Écouvillonnage, sanguin EDTA, sanguine hépariné, sperme, tissu |
| Mode of Inheritance | |
| Chromosome | |
| Year Published |
Informations générales
Fanconi Syndrome (FS) is a potentially severe kidney disorder that can cause dehydration, weight loss, and ultimately kidney failure. In dogs, the disease occurs in the Basenji, where it is caused by a recessive mutation to the gene FAN1.
Caractéristiques cliniques
Symptoms for affected dogs can vary in severity, from a total lack of apparent symptoms to major kidney-related defects. Severely affected dogs present with thirst, excessive urine production, glucosuria, dehydration and weight loss, which can progress to kidney failure. Age of onset can be anywhere between young adulthood to nine years old.
Additional Information
Références
Pubmed ID: PhD thesis University of Missouri
Omia ID: 2683