€57,48 €47,50 hors TVA
Inherited Myopathy of Great Danes (IMGD) a.
10 working days
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Caractéristiques
| Breeds | |
|---|---|
| Gene | |
| Organ | |
| specimen | Écouvillonnage, sanguin EDTA, sanguine hépariné, sperme, tissu |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Informations générales
Inherited Myopathy of Great Danes (IMGD) a.k.a. Centronuclear myopathy 2 (CNM) or HMLR, is a rapidly progressive muscle myopathy. IMGD results from a recessive mutation in the bridging integrator 1 (BIN1) gene. Affected dogs suffer from a progressive muscle atrophy and have a decreased ability to perform physical exercise. Only 20% of affected dogs survive to adulthood with acceptable quality of life according to previous research data.
Caractéristiques cliniques
IMGD presents at an age of onset around six months. Affected dogs are unable to perform physical exercise, display exercise-induced muscle tremors, and develop progressive muscle atrophy.
Additional Information
Références
Pubmed ID: 23754947
Omia ID: 1660